Daily Hours of Operation: 7 AM – 2 AM Details on open amenities and frequently asked questions can be. Poker alley and bingo parlor. The Route 66 Casino Hotel is now open. Enjoy our indoor pool that features an outdoor sundeck. Located less than 20 minutes from Downtown Albuquerque, you won't have to worry about traffic lights or commuters, the drive is straight and stress free highway. Thursdays. . The Route 66 Casino Hotel offers over 1, slot and video poker machines, 26 table games, a seat bingo hall, a dedicated poker room with 10 tables, five. Open daily from 7 AM - 2 AM! Under the initial reopening, you can Get Your Kicks on our slot machines and sports betting at The Book. More than 1, slots, craps, roulette and blackjack. Located less than 20 minutes from Downtown Albuquerque, you won't have to worry about traffic lights or. Saturdays. Sundays. Open 24 hours, 7 days a week! What's happening this April. International buffet, travel center, nightclub, 3-star hotel. Get your kicks at route 66! Stay and Go Play! Route 66 Casino Hotel. Route 66 Casino Hotel is a full-service casino, restaurant and hotel property located 17 miles west of downtown Albuquerque on Interstate 40 at Exit route 66 casino hours.